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16 Best Air Purifiers for Large Rooms To Fight Mold and Allergies

These air purifiers keep your air germ free, and some are on sale!

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The best air purifiers for large rooms improve the air quality of your entire house, removing the pollutants that make a space feel musty. Unless you like the idea of scrubbing walls and wiping away pet dander, you’ll definitely want one of these handy devices that make keeping a tidy home easier. They remove dust, pollen, and can even reduce your exposure to viruses without the aid of stinky chemicals.

Best Air Purifiers for Large Rooms Deals

Do air purifiers work in large rooms?

They do. In fact, some air purifiers can clear up to 3,000 square feet. That may not sound very large, but according to apartments.com, the typical room has an average of 200 square feet. Anything about 300 square feet is considered on the grander side of things.

You likely don’t just want to keep your room clean, though. If your home features an open floor plan, then an air purifier for a large room is worth considering. Sure, typical models work great for a bedroom or kitchen. But as you probably know, you have to move them around for the maximum benefit. The best air purifiers for large rooms can clear your kitchen, living room, and den all at once. Simply place yours in an entryway or by a window, where pollutants typically gain access to your home.

What are the best air purifiers for large rooms?

Does an air purifier help with Covid?

Air purifiers are great at removing dust, mold spores, and other allergens from the atmosphere. They can also snatch airborne viruses. If Covid is a major concern — and for most of us it is — you’ll be glad to know that one of the best air purifiers for large rooms has been shown to destroy SARS-CoV-2.

You may be familiar with the company Molekule. Their Air Mini air purifier features PECO technology, which uses free radicals to destroy pollutants on a molecular level. The technology was clinically shown to not only kill bacteria spores, E. Coli, and the RNA virus, but also Covid. Similarly, the Molekule Air Pro removes these virus strains, too. It can handle a space of 1,000 square feet, making it one of the best air purifiers for large rooms. It’s also one of my favorites!

For one thing, I love that it neutralizes germs. More air purifiers use a HEPA filter, which is very efficient at catching small particles. However, I want something that doesn’t just hold airborne nasties, but eradicates them. Secondly, I’m all for its sleek capsule-like design. Anything that improves the health of my home and fits in with my modern decor is a win-win in my book.

Where is the best place to put an air purifier? 

The best air purifiers for large rooms work best in centralized locations, according to Dilip Goswami, Molekule’s co-founder and CTO. “We always recommend running your air purifier for 24 hours a day, [so] that your air is continually being cleaned,” he says.

Although that may sound like a lot, it’s the best way to keep a toxin-free zone. “New pollutants can enter rooms as people and pets make their way through your space,” explains Goswami. He also cites open windows and new furniture as entryways for allergens and chemicals.

If you often wake feeling stuffy, then you may intuitively know air purifiers are great near your bed. Goswami calls this the sleep breathing zone. “We recommend placing [one] close to your bedside at night… it helps you wake up feeling refreshed and ready to go in the morning.”

According to the journal of Allergy, Asthma, and Immunology, dust mite allergies can get worse as we rest. Stationing an air purifier in your room where its not obstructed by a door or walls can help you breathe easier, which improves sleep.

What is the best air purifier on the market for large rooms? 

There are lots of options when it comes to the best air purifiers for large rooms. Nearly all use a HEPA filter in conjunction with multiple filtration systems to trap dust, and improve the air quality. And some are refreshingly quiet and stylish.

The LEVOIT Air Purifier is a great example. Its premium three-stage filtration system makes it a master at removing anything you don’t want in your lungs. It can grab large particles, like lint or hair, but it also removes mold spores and tinier pollutants.

If you’re a fan of the Dyson Purifier Cool Formaldehyde TP09, then you’ll love the Medify Air MA-40. It can clean a space of 840 square feet (Dyson only does 180), and absorbs toxins like lead dust and paint pigment. It also comes with the option to include UV-C light for no additional cost.

Whether you have allergies, pets, or want to decrease your chances of getting sick, there are more than a dozen air purifiers that can help. I won’t reveal here which made the number one spot — you’ll have to read the list — but I will say that no matter if your room is comfortably cozy or super sized, there’s a device that will keep it fresh and germ free.

Looking for even more options? Check out our other air purifier recommendations:

See more of our best product recommendations.

Best Air Purifiers for Large Rooms

TruSens Air Purifier

Best overall air purifier for large rooms
Best Air Purifiers for Large Rooms
Amazon

Buy from Amazon, $229

Why we like it:

  • Includes UV-C light to kill bacteria
  • Dual-airflow technology
  • Covers 1,425 Square feet

No dust mites get past the TruSens Air Purifier. In fact, the same can be said for mold spores, dander, and other gross things. Its 360 degree DuPont True HEPA filtration system pulls particles in from every direction and locks them in. The device comes with a sensor pod that reports contaminants to the purifier. As they’re pulled in, they’re hit with a UV-C light – viruses, you’ve been warned!

Designed with dual-airflow technology, the machine is 24 percent more effective at dispersing clean air than its counterparts. It’s easy to operate, and you can basically just press a button and let it do its thing. However, if you’re curious about what it’s up to, you can view air reports on the backlit LED screen.

Promising review: “My main reason for purchasing was for an allergy cough that I couldn’t shake. Within a day [with the air purifier], my cough was almost nonexistent…I love the air quality sensor.”

Molekule Air Pro

Best large room air purifier for covid
Best Air Purifiers for Large Rooms
Molekule
16% off!

Buy from Amazon, $1,041.99

Why we like it:

  • Destroys viruses
  • Detects humidity and chemicals
  • 360 degree air intake

If there’s one drawback of air purifiers it’s that they can release contaminants when changing their filter. That’s the last thing you want when germs are concerned. The Molekule Air Pro’s PECO technology uses free radicals to kill viruses like Covid, which means nothing nasty escapes its clutches. It pulls in air from every angle, reading the room for chemicals and micro-fine particles from food and smoke. Two auto protect modes adjust airflow and noise, so you can run the purifier even while sleeping. The machine can even read for humidity. Although it can’t get rid of that (yet), moisture does create mold. If something in your home is dampening the atmosphere, the Air Pro will be the first to let yo know.

If you love the Molekule Air Pro, don’t forget to check out the Molekule Mini+, which is also on sale for Prime Members!

Promising review: “I was very nervous when two family members returned home testing positive for Covid after a holiday visit. We followed all CDC recommendations for the isolation and quarantine periods, but I wasn’t sure how much of an impact our Molekule would have. I’m so happy that I managed to avoid infection, and I believe our investment in the Air Pro paid off. During the winter we always have trouble with respiratory infections, but this year has been different thanks to our Molekule.”

Coway Airmega 400

Best conway air purifier for large rooms
Best air purifiers for mold.
Amazon
Prime deal: 49% off

Buy from Amazon, $672.21

Why we like it:

  • Can clean rooms as large as 1,560 square feet
  • Has HEPA filter and UV-C light
  • Multiple noise level options

This is often cited as one of the best air purifiers for large rooms, and we agree. More than 1,600 customers on Amazon love it. The Conway Airmega 400 can clean spaces of 1,560 square feet, and its True HEPA filter catches particles as small as .1 microns. Its pollution sensors alert you of contaminants, changing colors as the air becomes cleaner. There are five different fan modes, and is quietest at the lowest setting. It also runs for up to eight hours a day. Another perk? Filters are machine washable.

Promising review:We’ve owned Airmega for about two months. It sits in a room next to the kitchen and backyard sliding door. When strong kitchen odors are present, the Airmega turns into high gear automatically and its light changes to red. I was opening a delivery package that was filthy and dusty about 10 feet away from it, and again it sensed the flying dust and kicked into high gear. Most of the time it runs on the lowest setting and is super quiet.”

Medify Air MA-40 Air Purifier

Best HEPA air purifier for large rooms
Best Air Purifiers for Large Rooms
Bulbs
24% off!

Buy from Amazon, $264.99 (was $349)

Why we like it:

  • Comes with a H14 and UV-C light option
  • Honeycombed carbon filter
  • Cleans 840 square feet

The MA-40 Air Purifier is Alcatraz as far as germs are concerned. Its three-part filtration system grabs dust mites, spores, and airborne bacteria you didn’t even know were there. A little taller than the MA-25 model, you have the option of choosing this model to have an H13 or H14 filter. The latter includes a UV-C light. Regardless of which you choose, the machine can run eight hours uninterrupted, and also has an ozone-free ionizer to remove smells. From pet dander to asbestos, nothing unfriendly will roam your halls again.

Promising review: “The unit efficiently removes dust, dander and particles from our bedroom where our two dogs lie on the floor on either side of our bed. My allergies were out of control. This purifier has eliminated the need to dust daily, and my itchy burning eye problem is almost nonexistent.”

Medify Air MA-25 Air Purifier

Best portable air purifier for large rooms
Best Air Purifiers for Large Rooms
Medify Air
20% off!

Buy from Amazon, $159.99 (was $199.99)

Why we like it:

  • Has a HEPA H13 filter
  • Only weighs 7.8 pounds
  • Covers 1,000 square feet in one hour

If you want your indoor air quality to be pristine, choose air purifier with a HEPA filter. But if you want your atmosphere immaculate, you want a HEPA H13 or higher. It means your air filter is medical grade, and just a tad more efficient at catching microscopic bits. For example, the MA-25 Air Purifier uses a H13, and can hold particles .1 micron small. That’s finer than a single strand of hair! The lightweight device fits nicely on countertops and bedside tables. Better yet, give it an hour and it can clean a room of 1,000 square feet. The design includes a child lock, so grandkids or pet paws can’t get at the three-speed fan inside. Bonus: When on night mode it automatically dims its screen and runs quietly.

Promising review: “I love it! I have COPD and animals that stay in my room. The MA-25 has allowed me to sleep and breathe so much more comfortably. I wake up feeling rested [like] never before.”

Shark Air Purifier 4 

Best Large Room Air purifier for Mold
Best Air Purifiers for Large Rooms
Bed Bath & Beyond

Buy from Amazon, $89.99

Why we like it:

  • Pulls in water droplets
  • Operates with remote control
  • Cleans 1,000 square feet

Moisture and mold are BFFs, according to the CDC. To avoid a swampy situation, place the Shark Air Purifier 4 near bathrooms or in your basement. It detects and pulls in water droplets, stopping fungi growth before it starts. Its HEPA filter can last up to a year, and includes a NANOSeal filter, which keeps spores and viruses from escaping when changing it out. Four fans with four different speeds evenly distribute clean air throughout the space, making it smell crisp. Happy customers on Bed Bath and Beyond love its luxe design and how quiet it is.

Promising review: “Wow is all I can say. When I started to cook dinner I set it by my kitchen, and in no time the numbers changed and it [adjusted itself]. [Shorty after], all the cooking odors were gone. This has never happened with my old air purifiers. They would at some point get the air clean but would take hours to do so. I love the fact It looks super high-end. There is basically no noise to it.”

Honeywell PowerPlus Air Purifier

Best power saving air purifier for large rooms
Best Air Purifiers for Large Rooms
Home Depot

Buy from Amazon, $141.55

Why we like it:

  • Offers four cleaning levels
  • Color coded air quality reader
  • Automatic cleaning mode

Is your furniture always dusty, no matter how much you clean? Here’s your solution: Honeywell PowerPlus. It offers four levels of purification. Select the microscopic particles setting to remove bacteria. The pollen level gets rid of allergens. Opt for a general clean on days your home feels musty, but turbo is what you want when you’ve burnt the family roast. The LED screen flashes different colors to indicate the air quality. Green, and you’re good to go. Yellow isn’t so hot, and red is, well, you know. The air purifier is Energy Star approved, and can be programmed to turn off after eight hours.

Promising review: “The Honeywell air purifier is a solid air filter. I noticed since I started using it that my kids allergies have instantly improved. I really liked the feature that tells the air quality. I noticed ours went from good to poor within minutes of putting an oil diffuser in room. This unit runs very quiet and has auto off and on. Just plug in and enjoy [clean] air.”

LEVOIT Air Purifier

Best LEVOIT air purifier for large rooms
Best Air Purifiers for Large Rooms
Amazon

Buy from Amazon, $299.99 – Use coupon on Amazon, save $30!

Why we like it:

  • VortexAir technology
  • HEPA H13 filter
  • Energy Saving

Clear the air with the energy saving LEVOIT Air Purifier. It’s powerful enough to cover over 1,500 square feet, and it’s tough on smells and allergens. Armed with an HEPA H13 filter, the purifier uses VortexAir technology to pull polluted air into its core. AirSight sensors read the room, automatically adjusting fan speeds. Although a mighty machine, it only uses 48 watts of power on its highest setting. Download the VeSync app to control from your smart phone or use it with Google Assistant or Alexa.

Promising review: “I got this hoping it would help my older home, which is always dusty. I’m pleased that there is less dust, and that the house even smells fresher. My daughter came home for a long weekend, and she commented that for the first time her sinuses were not acting up. I love it, and am sorry I didn’t purchase it years ago.”

Blueair Blue Pure 211+ Air Purifier

Best allergy fighting air purifier for large rooms
Best Air Purifiers for Large Rooms
Home Depot

Buy from Amazon, $298.99 (was $319.99)

Why we like it:

  • Cleans air five times per hour
  • Includes activated carbon filter
  • Covers 600 square feet

When spring ushers in, so does allergy season. Rather than deprive yourself of open windows, make room for the Blue Pure 211 + Air Purifier. It sucks in 99 percent of sniffle-producing particles, like pollen and pet dander. The device is super simple to use with its one-touch system, and has three fan settings that help it clean a room five times in one hour. Since I like to cook aromatic food (that’s my fancy way of saying broccoli and other stinky vegetables), I appreciate its odor-trapping carbon filter. To make it more impressive, it’s Energy Star rated. This can also be purchased at Home Depot, where it comes with a two year warranty.

Promising review: “I’ve been struggling with severe allergies and post nasal drip. I researched air purifiers and discovered Blueair. While I waited for it to arrive, I dusted, vacuumed and purged anything that wasn’t being used. Within two days of it arriving and running on high, I could literally smell the difference. After three weeks my home’s air is noticeably lighter. I’m breathing better, and the allergies are getting under control.” 

Air Oasis iAdaptAir-L 

Best tower air purifier for large rooms
Best Air Purifiers for Large Rooms
Amazon

Buy from Amazon, $633.45

Why we like it:

  • Fits neatly in corners
  • Cleans air and surfaces
  • Only 20 pounds

Air isn’t the only place pollutants like to roam wild. When pollen or dust falls, where do you think they go? On your surfaces, of course. Fortunately, the iAdapt Air-L can remove them, making your home cleaner and safer. It has a HEPA filter to grab small allergens, and its UV-C light vaporizes bacteria from food fumes or coughing visitors. It’s great for rooms of 850 square feet or less. Look forward to the eradication of musty closet smells and stuffy noses.

Promising review: “The Air oasis iAdaptAir-L has been fantastic in our large master bedroom that connects to our large bath and closet. It keeps the air clean, fresh, and mold free in a humid living environment. We are very pleased!”

Blueair Blue Pure 311 Auto Purifier

Best air Purifier for large rooms with easy operation
Best Air Purifiers For Large Rooms
Bed Bath & Beyond

Buy from Amazon, $249.99

Why we like it:

  • One button performance
  • HEPA filter
  • Cleans rooms up to 388 square feet

If you hate messing with gadgets of any sort, you’ll love the Blueair Blue Pure 311 Auto. All you have to do is turn it on, and the machine automatically begins cleaning. You may as well toss your allergy medicine out now, because you probably won’t need it after making this your housemate. It can remove 99.9 percent of airborne particles, including pollen, dust, and even germs. Featuring three levels of filtration, it’s less than seven pounds, and quiet enough to keep running while you sleep or work. Perfect for the master bedroom or den, in a mere 12 minutes it can remove VOCs from a room of 388 square feet! However, if you have a larger space that needs some help, it can also remove airborne nasties from a room of 1,862 square feet in a single hour. Now that’s nothing to sneeze at!

Promising review: “I have had the Blue Air 311 Auto for about one year, and it keeps my master bedroom smelling fresh, even though there are two other smokers in the house. I recently purchased [another] for the living room, and it has done [fantastic] at keeping the cigarette smoke out of the font of the house.”

Alen BreatheSmart FLEX

Best quiet air purifier for large rooms
Best Air Purifiers for Large Rooms
Alen
Save $100!

Buy from Alen, $224 (was $349)

Why we like it:

  • Extra long cord
  • Includes HEPA H13 filter
  • Cleans 700 square feet in 30 minutes

Air purifiers can help you wake less congested and more refreshed. And the same is true for the BreatheSmart FLEX, but it also helps you fall asleep. It uses ambient or pink noise, which may trigger deeper sleep. The purifier also has a H13 filter that can clean a large room in half an hour. Its fan has four speed settings, and it comes with a lifetime warranty. No matter if you’re concerned about dust, smoke, or pollen, this device will stop it before it gets to you.

Promising review: “I’ve been sleeping so much more soundly since purchasing this. I’ve only had it a few weeks, but I can notice a difference with air quality and smells.”

AIRTOK Air Purifier

Best affordable air purifier for large rooms
Best Air Purifiers for Large Rooms
Amazon

Buy from Amazon, $119.99

Why we like it:

  • Has a HEPA H13 filter
  • Can be voice activated
  • Cleans 1,100 Square Feet

One of the best air purifiers for large rooms is the AIRTOK. Along with being under $200, it can remove VOCs and other no-nos from a 1,100 square-foot space. Leave it in your garage to remove paint fumes or let it run in your home’s entrance to catch pollutants sneaking through the door. It has an HEPA H13 filter in the center, so you know it can catch the smallest particle. The pre-filter grabs fine fibers, while the carbon filter takes odors out of the air. The machine comes with a remote control, but can also be programmed to be activated with your voice. Run it for two, four or eight hours at a time.

Promising review: “This air purifier works great and definitely helps with dust and allergens in the house. We have this in a large master bedroom and it works well. I like using the high speed instead of a fan at night for white noise while I sleep. The other speeds are great if you want it a little quieter.”

Puraclenz P3000 Air and Surface Purifier

Best space saving air purifier for a large room
Best Air Purifiers for Large Rooms
Puraclenz

Buy from Puraclenz, $399.99

Why we like it:

  • Can be mounted on wall or tables
  • Covers 3,000 square feet
  • Uses PCO technology to clean air

Not all air purifiers for big spaces have to be clunky. In fact, the best air purifiers for large rooms can easily blend into your decor. The Puraclenz P300, for example, looks like a piece of art. It’s effective on tabletops, but can even be mounted on your wall. Whatever you choose, you’ll be pleased with how great it is at cleaning your air. It has NASA designed PCO technology, that creates ions with UV-C light to neutralize bacteria and smells. A foam pre filter catches larger pieces of debris. We’re sure you’ll love it, but if you don’t, you can return within 30 days and get a full refund.

There are no reviews yet. You could be the first!

BISSELL air400

Best asthma friendly air purifier for large rooms
Best Air Purifiers for Large Rooms
Wayfair

Buy from Walmart, $219 (was $258.61)

Why we like it:

  • Cleans a 1,200 square feet in one hour
  • Easy-to-read monitor
  • Simple set up

Wanting to keep a compromised immune system strong is a great reason to get an air purifier, and this one from Bissell doesn’t disappoint. It can clean 1,200 square feet three times in a single hour, and its 20,000-hour DC motor circulates clean oxygen quickly. That means while it’s sucking in dander and dust, you’re getting fresher, higher quality air at the same time. It includes an activated carbon filter to trap smells, and the easy-to-read display helps you track what’s happening in the atmosphere.

Promising review: “I haven’t found anything I don’t like about this air purifier… The Bissell seems to control any smoke or cat odors. I have previously used scented candles to mask those, but think those days are over now!”

BluDri Air Scrubber

Best commercial air purifier for large rooms
Best Air Purifiers for Large Rooms
Home Depot

Buy from Home Depot, $619

Why we like it:

  • Great for heavy duty cleanup
  • Multiple filtration systems
  • Cleans an entire house

Planning on revamping your home? BluDri’s Air Scrubber was made to tackle heavy air pollution, like pain fumes and smoke. Whether you’re repainting or turning your basement into a theater, the industrial standard machine can handle saw dust, mold damage, and more. It has three different filters to catch hair, smells, and debris, and is powerful enough to cleanse an entire house. If you’re not the type to buy multiple purifiers or move one from room to room, this is definitely the one for you.

Promising review: “I use this to do drywall repair and installation as well as mold remediation and dust control. It works great!”

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