Christina Applegate, 54, Reportedly Hospitalized Amid MS Battle: What We Know About Her Health
Her rep responds as fans question what’s behind this latest health update
Key Takeaways
- Christina Applegate, 54, was reportedly hospitalized, though details remain unconfirmed.
- Her rep declined to confirm her condition, citing her complex health history with MS.
- The actress has been open about frequent hospital visits since her MS diagnosis.
Christina Applegate, 54, has been hospitalized, according to a new report. The Dead to Me actress, who has been battling the effects of multiple sclerosis (MS) since 2021, was admitted to the hospital in Los Angeles in late March, TMZ reported from “sources with direct knowledge” on April 16. It’s unclear whether her hospitalization is related to her MS diagnosis.
Christina Applegate’s rep on rumors the actress is hospitalized
Applegate’s rep Ame Vanlden declined to comment on whether Applegate was hospitalized or her current medical status. “She’s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast,” her rep told USA TODAY.
Applegate’s MeSsy podcast, which she cohosts with fellow actress Jamie-Lynn Sigler, 44, who also has multiple sclerosis, went on a short hiatus at the end of March. They announced the podcast would be taking a “short break for the next few weeks” while Sigler and Applegate promoted their books.
Woman's World Answers
Applegate opened up about living with MS in her memoir
The former Married With Children star told USA TODAY in late February that she was “sick as a dog” from a viral infection, speaking from bed for an interview about her memoir, You With the Sad Eyes. She recalled not realizing how difficult it would be unearthing “all of these things that were so unbelievably horrifying in my life,” which she has stuffed “into what I call my trauma ball in my stomach.”
“It was like having a therapy session, and I couldn’t stop,” Applegate shared in the interview. “I didn’t judge myself and I didn’t want to judge myself, and I didn’t want to edit myself either.”
Christina Applegate was previously hospitalized amid MS battle
The actress previously said in August that she was hospitalized for a kidney infection. She shared the revelation on an episode of her MeSsy podcast, which she recorded while still in the hospital.
“I’m holding in [a] bag o’ tears right now,” she said on the Aug. 5 episode. “Just [a] bag o’ tears. I sometimes fall into the nurse’s arms like a freako, just crying.”
In a statement provided to USA TODAY at the time, Applegate said she has returned home since recording the podcast and has “been treated for the kidney infection” after seven days in the hospital.
And in March 2025, Applegate revealed on her podcast that she’s been in and out of urgent care constantly since being diagnosed with multiple sclerosis.
“For three years, since I was diagnosed, I’ve been in the hospital upwards of 30 times,” Applegate said. “That is unimaginable, OK? They’ve done every test known to man on me, put so much radiation into my body from CT scans to everything else.”
What is MS? Multiple sclerosis symptoms to watch for
MS triggers a breakdown of the protective covering of nerves, according to the Mayo Clinic. The condition can cause symptoms such as numbness, weakness, difficulty walking, slurred speech and vision changes. There is no cure.
Though symptoms may vary from person to person, and depending on the location and severity of the nerve damage, some lose their ability to walk or move on their own. Others may go for long stretches without new symptoms, what’s known as remission.
Contributing: Brendan Morrow, Anna Kaufman, Erin Jensen, USA TODAY
This article originally appeared on USA TODAY: Christina Applegate’s rep responds to report of hospitalization via Reuters Connect
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