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16 of the Best Gut-Healing Probiotics for Women Over 50

Add any of these probiotics to your routine for better gut health!


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By now, you’ve probably heard of probiotics — those little live microorganisms that work to improve or restore our gut bacteria. But not all probiotics are created equally. As with multivitamins, it’s important to identify which types are specifically targeted for your nutritional needs. The best probiotics for women over 50 will help keep your gut healthy and balanced and promote a healthy immune system. Find out what probiotics can do for you, how to shop for them, and some of our favorite probiotic brands for older women.

What are probiotics?

According to New York-certified dietitian nutritionist Alissa Rumsey, “Probiotics are beneficial bacteria that replenish our body’s micro-biome with healthy cultures while helping to control the growth of harmful bacteria in our gut.” 

We know what you’re thinking — isn’t bacteria bad? In reality, our bodies are covered in bacteria, most of it good, some of it bad. Probiotics are the good guys that work to improve our immune function, protect against the risk of infection, and aid in nutrient absorption by keeping the gut and digestive system happy and healthy; something that’s especially vital to our bodies as we age.

What do probiotics do? 

While everyone could benefit from probiotics — we’ve all had bad stomach days! — those suffering from digestive disorders may find them especially helpful. “Probiotics are thought to play a role in preventing and treating certain conditions, such as diarrhea, irritable bowel syndrome, ulcerative colitis, and Crohn’s disease,” says Rumsey.

While these wonderful bacterial organisms can be found naturally in foods such as yogurt, sauerkraut, and kefir (to name a few), they also come in supplemental form.

What should women over 50 look for in a probiotic?

The best probiotics for women over 50 will be specific to your needs. That might include digestive issues, like diarrhea and leaky gut, but that could also mean general health issues such as urinary tract health or weight loss.

According to the American Nutrition Association, the recommended daily intake for probiotic supplements can range from 1 billion colony forming units (CFU) to 100 billion per day. If you find your gut and overall health to be pretty good, then a low number of CFUs may be all you need.

However, since our immune systems weaken as we age, a higher number of CFU may be necessary for women over 50 in order to stay healthy and see significant results. A probiotic with a CFU ranging from 25 to 50 billion is a great place to start.

As with any supplement, it’s important to consult your doctor before adding a probiotic to your daily vitamin regimen.

The Best Probiotics for Women Over 50 

This content is not a substitute for professional medical advice or diagnosis. Always consult your physician before pursuing any treatment plan.

Garden of Life RAW Probiotics Women 50 & Wiser (85 Billion CFU)

Best Probiotic for Older Women
best probiotics for women garden of life

Buy on Vitacost, $42

Why we like it:

  • Supports colon, thyroid, and vaginal health
  • Offers 85 billion CFUs
  • No binders, fillers, or carriers

If you’re looking for one of the most well-rounded probiotics on the market, you’ve come to the right place. Garden of Life’s RAW Probiotics Women 50 & Wiser offers an impressive 85 billion CFUs and is comprised of 33 original probiotic strains, making it one of the most concentrated supplements on this list. Uniquely-formulated with the needs of mature women in mind, this probiotic supports colon, thyroid, and vaginal health. It also gives a boost to your overall digestive region with enzymes to break down lactose and casein (a protein found in milk) — something that becomes increasingly difficult as we age. Better yet, with no binders, fillers, or carriers, what you see is what you get.

“This is a good, complete Probiotic. Have been using it for almost a year and it has really helped in digestion. As a bonus, it helped me lose a few pounds. The price is really good through Amazon — I highly recommend this to women 50 and wiser.”

Vitamin Bounty Pro 25

Best Probiotic For Beginners

Buy on Amazon, $18

Why we like it:

  • Made with 13 different probiotic strains
  • Delays probiotic release for better absorption

If you’re unsure about the number of CFUs you should begin your probiotic journey with, we recommend Pro 25 from Vitamin Bounty. Formulated with 13 different probiotic strains and 25 billion organisms per capsule, this supplement is in a league all its own. A patented delayed release protects organisms from erosive stomach acid to make sure the bulk of those cultures are absorbed into your digestive system — not your stomach. And, should you find that 25 billion CFUs aren’t getting the job done, you can always up your count with the brand’s Pro 50 formula ($27), which is made with 50 billion organisms per serving.

One reviewer said they feel their “best” after using this probiotic. “Since I’ve started taking them, I feel great! In the past I didn’t want to spend the money on probiotics but it is definitely worth it to spend a little extra money to feel my best. I highly recommend this product.

Zenwise Health Digestive Enzymes

Best Probiotic for Leaky Gut

Buy on Amazon, $18

Why we like it:

  • Made with a blend of natural, plant-sourced enzymes
  • Strengthens your digestive system
  • Helps with leaky gut and IBS

This Digestive Enzymes supplement from Zenwise Health is a far cry from your typical probiotic. Made with a blend of natural, plant-sourced enzymes, inulin prebiotic (inulin is a starch-like substance found in fruit while prebiotics are the food that probiotics feed on), and 1 billion CFUs of multi-strain probiotics, this vegetarian capsule aims not only to ease stomach discomfort, but to strengthen your digestive system. A strong digestive system means your body’s absorption properties will improve, making this one of the best probiotics for issues such as leaky gut (a condition in which bacteria and toxins are able to “leak” through the intestinal wall), irritable bowel syndrome (IBS), and other gastrointestinal complications. Better yet, when your digestive system works properly, it takes less energy to process food, so you’ll feel better overall, too.

One reviewer described these as a “godsend” and how “taking these probiotics regularly, I am having much better quality of life. They’ve even helped me lose some weight.”

Renew Life Ultimate Flora Probiotic Adult 50+

Best Probiotic for Elderly

Buy on Amazon, $16

Why we like it:

  • Contains 12 strains of Bifidobacteria (for digestive health)
  • Receive 30 billion active cultures per serving
  • Free of Gluten, dairy, and soy

One of the most important types of bacteria found in a healthy digestive system is Bifidobacteria. Unfortunately, the amount of Bifidobacteria found in the gut declines with age. This can lead to everything from occasional irregularity to an overall decline in nutritional absorption. To prevent this, reach for Renew Life’s Ultimate Flora probiotic. With 12 strains of Bifidobacteria and 30 billion active cultures per serving, you’ll be feeling like a new woman in no time.

“I’ve been taking one pill a day as suggested, everyday for the past month now, and I truly feel great. My body is stronger, I am more focused on things I do during the day, I am in a better mood, right from the start in the morning and don’t go through the afternoon fatigue, like I used to before.

Replenish the Good Daily Probiotic

Best Probiotic for Acid Reflux

Buy on Amazon, $22

Why we like it:

  • Helps balance the digestive and intestinal systems
  • Promotes brain and immune system function
  • Aims to elevate mood and energy levels

Suffering from acid reflux? You might want to put down the antacid and pick up a probiotic. Acid reflux, also referred to as gastroesophageal reflux disease (GERD), is a condition in which stomach acid flows back up into the esophagus, causing what is commonly known as heartburn. Not only can this condition be uncomfortable, it can cause serious, irreversible damage to the lining of your esophagus if left untreated. Acid reflux is a result of the digestive system being out of whack, so to help calm your stomach down, try Replenish the Good’s daily probiotic. This bacteria-rich probiotic will allow you to balance your digestive and intestinal systems in no time.

Take it from one reviewer, who wrote, “I have dealt with acid reflux since I was a teenager. I was popping antacids like candy. Now that I take this probiotic, I no longer have to rely on antacids for relief.”

Vitamin Bounty Pro-Daily Immunity

Best Probiotic for Immunity
Immune Support Probiotics with Vitamin C & Zinc + Prebiotics

Buy on Amazon, $15

Why we like it:

  • Contains 10 specific strains of helpful bacteria
  • Provides vitamin C and zinc
  • Free of dairy, GMOs, and gluten

When researching probiotics, you may uncover the astounding fact that “a huge proportion of your immune system is actually located in your GI tract.” That means that the first step in preventing the common cold isn’t about lemon and echinacea, per se, but probiotics. If you feel sickness coming on, reach for Vitamin Bounty’s Pro-Daily Immunity. While many probiotics can help boost your immune system, not all are specially formulated to up your body’s natural defenses like this one, with features 10 specific strains of helpful bacteria plus a healthy dose of vitamin C and zinc.

One reviewer praised how easy it is to taking noting, “The pills are easy to swallow, there is no strange taste, I don’t experience any stomach discomfort, and they seem to play well with my other supplements.

Align Probiotics Supplement

Best Doctor-Recommended Probiotic

Buy on Amazon, $44

Why we like it:

  • Doctor recommended!
  • Naturally strengthens your digestive system
  • Helps with bloating, gas, and stomach discomfort

If there’s one probiotic you’ve already heard of, it’s Align — and for good reason! Formulated to naturally help strengthen your digestive system, this popular supplement contains Bifidobacterium infantis 35624, a unique probiotic strain that’s been shown to provide optimal digestive support and help in the treatment of certain digestive issues. 

It also comes doctor recommended. Shauna Carrigan of Lorraine Kearney Nutrition, RD., recommends Align to patients — especially those with IBS. “It has been studied clinically for its beneficial effects on healthy digestion; well-designed random control trials have shown improvements in IBS symptoms,” she says. 

Nature’s Way 3-in-1 Women’s Probiotic Gummies

Best All-In-One Probiotic

Buy on Amazon, $16

Why we like it:

  • Reduces occasional bloating
  • Supports digestive and vaginal health

A women’s probiotic that supports your vaginal and digestive health? Count us in! It comes in a delicious orange-flavored gummy form and helps you take charge with a 3-in-1 approach to support digestive and vaginal health that can also reduce occasional bloating. They contain the clinically studied probiotic strain Unique IS-2® to reduce occasional bloating and digestive discomfort, plus add good bacteria to the GI tract, promote digestive regularity, and help support balanced vaginal flora.

Happy Customer: “So when I first tried these gummies, I was like ‘there is no way I could eat these every day,’ but let me tell you, by the third day, I was eating them no problem. I guess I was used to those prenatal gummy vitamins with the sugar on them, so these were a bit of a changeup, but now I actually like the taste of them. (I switched over since I am not pregnant and don’t plan to be). The bottle suggests eating two per day and they’re small enough that its easy to do. They’ve caused no intestinal issues for me. I’m just happy to be getting my vitamins!”

Replenish the Good Women’s Probiotic

Best Probiotic for Mental Health

Buy on Amazon, $22

Why we like it:

  • Contains 6 billion CFU
  • Helps provide yeast infection relief
  • Promotes a healthy urinary tract

What supplement contains a six billion CFU count, can provide yeast infection relief, and promotes a healthy urinary tract to boot? Replenish the Good’s Women’s probiotic! This American-made supplement consists of only the best natural ingredients for women, as well as the daily recommended doses of vitamin D3, cranberry extract, and urinary tract fortifier D-mannose. And, with six powerful probiotic strains that have been shown to elevate energy and mood, it’s also one of the best probiotics for mental health.

Happy Customer: “This product honestly changed my life! I tried another probiotic before this that didn’t do much, but with this one I felt a big difference. I bought this as a way to prevent yeast infections, and discovered that taking this did more than that. I normally have really bad allergies during the spring, and for the first time in years I have no allergy symptoms whatsoever. I also used to get colds really easily since I work in a small office, and since taking these I haven’t gotten any…this product is honestly worth trying!

MaryRuth Organics Liquid Probiotic

Best Liquid Probiotic

Buy on Amazon, $40

Why we like it:

  • Best if you don’t like swallowing pills
  • All-natural
  • Contains 14 probiotic strains

No matter how old you get, some people just have a hard time swallowing pills. If those pesky capsules have been making you steer clear of probiotics, MaryRuth’s liquid probiotic may just be your saving grace. This all-natural and US-made supplement has a long shelf life, tasteless quality, and 14 pure probiotic strains. Best of all, however, is its inclusion of Lactobacillus Rhamnosus — a bacteria strain that’s known for its benefits for liver.

One reviewer “adores” the probiotic and “look forward to taking everyday! I have benefitted so much from using the liquid probiotic. Ever since I was young I always had a bloated belly and especially after eating I would look large and feel very sluggish. The probiotic has reduced my bloating to the point I had stopped thinking about the bloating…I also feel now that my micro biome is achieving a healthier status, my moods have stabilized, and my mental rumination is greatly reduced. The probiotic has helped me feel solid, stabilized and eating is comfortable again!

Jarrow Formulas Saccharomyces Boulardii + MOS

Best Probiotic for Inflammation

Buy on Amazon, $34

Why we like it:

  • Helps with eczema, skin inflammation, and more
  • Contains 5 billion CFUs
  • Aims to activate the immune system

One of the most popular probiotics from the last 30 years is Saccharomyces Boulardii. Used to treat everything from Crohn’s disease and ulcerative colitis to skin inflammation and eczema, this powerful organism has become a staple for a reason. It can be found aplenty (think five billion CFUs) in Jarrow Formulas’s top-rated supplement, which has an added dose of MOS (mannan oligosaccharides) that activate the immune system in mammals, making it one probiotic you’ll want to add to your diet, stat.

One reviewer describes it as a “miracle worker in a bottle,” especially for stomach issues. “For me, this is a miracle worker against extreme stomach issues. The more I read about this amazing yeast, the more I am convinced everyone should have some when abroad, just in case they get stomach problems.”

Nature’s Way Fortify Women’s Probiotic

Best Probiotic for IBS

Buy on Amazon, $21

Why we like it:

  • Made with 50 billion CFU
  • Supports digestive issues and vaginal health
  • Improves most IBS symptoms

With a CFU count of 50 billion, Nature’s Way’s Fortify is one of the most effective probiotics on this list. This extra-strength supplement features an original probiotic blend called Primadophilus, which is comprised of 50 percent more Lactobacilli than Bifidobacteria, to support general digestive issues, alongside vaginal health. Studies have shown that certain strains of Lactobacilli can even improve many of the symptoms associated with IBS, allowing you to say good riddance to your stomach issues in no time. Reviewers advise that because it’s considered “extra-strength” first-time users may notice some discomfort at first.

“These have helped me so much!! If you have stomach, gas, constipation issues, or have frequent yeast infections, probiotics are a must!! These are capsules, but they are very easy to swallow, and there is no taste at all. The first day I was bloated and my stomach hurt, but after that I felt so much better. Now I never miss a day. These are “extra strength” so if you’ve never taken a probiotic before you may have a few days of discomfort. I started with 20 billion and then changed to these ones. Great brand-I’ve tried several others as well.

Renew Life Ultimate Flora Probiotic

Best Probiotic for pH Balance

Buy on Amazon, $63

Why we like it:

  • Promotes healthy vaginal and urinary health
  • Contains 90 billion CFU probiotics
  • Supports healthy digestive system

When your stomach isn’t at its best, it can throw other things out of whack, too. That’s where Ultimate Flora by Renew Life comes in. This high-potency, 90 billion CFU probiotic is made with 12 strains of Bifidobacterium and Lactobacillus bacteria that will help with much more than your digestive system. Lactobacilli, in particular, also promotes healthy vaginal and urinary health, making it one of the best probiotics for a women’s pH balance.

“I have been using probiotics now for around six years. I have tried over six different brands and this one is my favorite of all the ones I have tried. It is effective and truly does work! I have taken one of these and within two to three hours my gut health has done a one eighty!”

Dr. Matthew #1 Probiotics

Best Probiotic for Eczema

Buy on Amazon, $23

Why we like it:

  • Eases eczema flare-ups
  • One serving contains 15 billion CFU
  • Replenishes gut flora

We’ve already discussed how probiotics can aid in decreasing skin inflammation, but did you know they can also quell symptoms of one of the most prevalent skin conditions among women over 50? Yep, we’re talking about eczema. According to the National Eczema Foundation, these friendly bacteria can help ease your flare-ups! While research is still ongoing, many have found that strains Lactobacillus Ramnonsus and L. Plantarum, which are found in this supplement from Dr. Matthew, can be particularly useful.

One Amazon buyer raved, “I have been using these for about a week now and I’ve noticed that my eczema is decreasing. Wish I found this stuff sooner!”

Align Probiotic, Yogurt Coated Probiotic Fruit Bites

Best-Tasting Probiotics

Buy on Amazon, $22

Why we like it:

  • Try it risk free!
  • 21 individually wrapped pouches of 5 bites
  • They don’t require refrigeration

Align Probiotic is the #1 probiotic brand recommended by doctors for over 10 years running and is recommended nearly 2X more than any other probiotic brand. These delicious yogurt-coated bites make adding probiotics to your diet simple! They’re packed individually so you can take them on the go or at home with your breakfast.

One Amazon buyer shared, “The pouches make it really convenient. Easy to carry everywhere. These are also absolutely delicious! Great way to incorporate probiotics into daily diet!”

Lifeway Low Fat Kefir With 12 Live Active Probiotic Cultures

Best Probiotic Protein Combo

Buy on Amazon, $6

Why we like it:

  • Easy to drink by itself or incorporate into protein shakes and smoothies
  • 11 grams of protein per serving
  • Because of the fermentation, those with lactose sensitivities can typically tolerate!

Yogurt is a great, convenient way to add probiotics to your daily diet, but kefir makes it even easier! With 25-30 billion colony-forming units, Lifeway Kefir has considerably more probiotics than most commercially produced yogurt, a wide variety of bioactive peptides, and it’s lactose intolerance friendly. Try the many flavors Lifeway Kefir offers!

One Amazon buyer says, “Love this stuff. If you are looking for a sugary kid drink, look elsewhere. This has a salty kind of taste, thick like milk mixed with plain yogurt. Filling, and I think healthier than those drinks marketed to older people that have sugar and flavors. You get your calcium, you get your protein, you don’t get high fructose corn syrup and colors and junk. I always keep a few bottles in the fridge.”

Want even more supplements for older women? Keep reading!

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